Is this actionable now?

upcoming. The current official Manifest page says applications will open in 2026 but gives no exact opening date or deadline.

Academic scientists proposing translational, high-risk deep-tech work; exact 2026 call rules remain unavailable until the application opens.

What burden and restrictions apply?

The current page emphasizes rapid review and no IP taken; earlier Manifest calls encouraged short quarterly updates, but current award terms must be checked. Funds support the proposed translational deep-tech research; current 2026 cost and overhead rules are not yet published.

What evidence exists?

The current page promises a 21-day decision and no IP claim. No 2026 application or award count is published.

Fifty Years — Manifest Grants

USD 25,000–100,000 grant; maximum two-page application and a stated decision within 21 days · Fifty Years (venture firm)

Grants from VC firm Fifty Years for academic scientists with translational, high-risk/high-reward 'deep tech' research ideas — spanning synbio/climate, AI safety, tools to accelerate biology, drug discovery, robotics, energy, and manufacturing. Current lifecycle: upcoming. Real economics: USD 25,000–100,000 grant; maximum two-page application and a stated decision within 21 days.

Tier 3deep-techsciencetranslational-researchgrants

Apply Official site Open in the live directory

Key facts

Funder	Fifty Years (venture firm)
Amount	USD 25,000–100,000 grant; maximum two-page application and a stated decision within 21 days
Decision time	The current page promises a decision within 21 days after a maximum two-page application.
Eligibility	Academic scientists proposing translational, high-risk deep-tech work; exact 2026 call rules remain unavailable until the application opens.
Restrictions	The current page emphasizes rapid review and no IP taken; earlier Manifest calls encouraged short quarterly updates, but current award terms must be checked. Funds support the proposed translational deep-tech research; current 2026 cost and overhead rules are not yet published.
Status	upcoming

Always confirm on the official page before applying — dates and terms change.

Application process

Wait for the 2026 application to open
Submit a proposal of no more than two pages
Complete rapid scientific review
Receive a decision within 21 days
Execute the funded translational project

Background

Fifty Years (venture firm) operates Fifty Years — Manifest Grants. This pass separates direct cash, repayable finance, credits, incentives and umbrella programs so later ranking does not compare unlike instruments. The current page promises a 21-day decision and no IP claim.

How the application really works

Wait for the 2026 application to open → Submit a proposal of no more than two pages → Complete rapid scientific review → Receive a decision within 21 days → Execute the funded translational project

Tips

Show direct fit with synthetic biology.
Show direct fit with climate.
Show direct fit with AI safety.
Show direct fit with biotechnology tools.
Show direct fit with drug discovery.
Show direct fit with robotics.
Show direct fit with energy.
Show direct fit with manufacturing.

Watch out for

Current lifecycle is upcoming.
The current page emphasizes rapid review and no IP taken; earlier Manifest calls encouraged short quarterly updates, but current award terms must be checked.
Funds support the proposed translational deep-tech research; current 2026 cost and overhead rules are not yet published.

Track record

The current page promises a 21-day decision and no IP claim.

No 2026 application or award count is published.

Frequently asked questions

Is this actionable now?: upcoming. The current official Manifest page says applications will open in 2026 but gives no exact opening date or deadline.
What is the real economic value?: USD 25,000–100,000 grant; maximum two-page application and a stated decision within 21 days
Who is eligible?: Academic scientists proposing translational, high-risk deep-tech work; exact 2026 call rules remain unavailable until the application opens.
How does selection work?: Wait for the 2026 application to open; Submit a proposal of no more than two pages; Complete rapid scientific review; Receive a decision within 21 days; Execute the funded translational project. The current page promises a decision within 21 days after a maximum two-page application.
What burden and restrictions apply?: The current page emphasizes rapid review and no IP taken; earlier Manifest calls encouraged short quarterly updates, but current award terms must be checked. Funds support the proposed translational deep-tech research; current 2026 cost and overhead rules are not yet published.
What evidence exists?: The current page promises a 21-day decision and no IP claim. No 2026 application or award count is published.

Sources

fiftyyears.com/manifest — Official current 2026 notice, amounts, proposal length, decision speed and IP rule (checked 2026-08-10)
www.fiftyyears.com/manifestclimate — Official prior-round operating context and public contact (checked 2026-08-10)